Hyperbaric oxygen therapy has been used for centuries but it has been accorded more scientific reasoning only recently. Ophthalmic applications of this therapy is an off label use of hyperbaric oxygen but results of its use in Central Retinal Artery Occlusion and many other devastating ocular infections is paving the way for increasing acceptability by ophthalmologists. Recent protocols of therapy are being enunciated and safer hyperbaric chambers are being manufactured to help patients and doctors use this hereto underutilised modality of treatment.