Delhi Journal of Ophthalmology

Immunological Basis of Symptomatology in Ocular Diseases

Upma Awasthi, Shalini Mohan
Ganesh Shankar Vidyarthi Memorial Medical College, Kanpur, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.

Corresponding Author:

Upma Awasthi MBBS, MS
Consultant Ophthalmologist
Phaco and Vitreo-Retina Surgeon
New Delhi 
Email Id:

Received: 16-SEP-2017 Accepted: 17-OCT-2017 Published Online: 27-FEB-2018

AbstractHypersensitivity reactions are our own immune responses to various triggering factors. These immune responses result in different clinical presentations of various ocular diseases. Various cytokines, interleukins are responsible for a myriad of symptoms and thus our therapy should be targeted on specific immunological pathways. In this article we have summarized various ocular diseases with the causative immune pathways thus simplifying the underlying cause. This article will help in understanding why similar looking diseases may have requirement for different modalities of treatment or why similar medications may work in different ocular diseases.
Keywords :ocular immunology, hypersensitivity reactions, ocular mast cells, immune reactions