Delhi Journal of Ophthalmology

A Rare Case of Keratomycosis Due to Myriodontium keratinophilum

Shivani Kochhar1, Vishnu Swarup Gupta1, Harinder Singh Sethi2, Malini R. Capoor2
1Dept. of Ophthalmology, Hamdard Institute of Medical Sciences and Research, New Delhi, India
2Dept. of Ophthalmology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.

Corresponding Author:

Shivani Kochhar 
D 614, Ram Vihar, Sector 30, 
Noida 201031, UP, India
Email id:

Published Online: 01-NOV-2018

Purpose: To report a rare case of keratomycosis due to Myriodontium keratinophilum, which has not been previously reported.
Materials and Methods: A 60 year old male patient with pseudophakic bullous keratopathy with rupture bullae and history of use of bandaged contact lens developed a corneal ulcer. Corneal scraping from the base and edge of the ulcer was obtained under slit lamp magnification and smear sent for various aerobic and anaerobic bacterial and fungal cultures such as Gram stain, Giemsa stain, KOH mount, Lacto-phenol Cotton-blue mount, culture on Brain-heart infusion based blood agar, chocolate agar and Sabouraud Dextrose Agar (SDA) to identify the type and time of growth to be able to diagnose the pathognomonic agent causing the keratitis.
Result: Positive smears and cultures from the corneal scrapings identified the causative agent as Myriodontium Keratinophilum. The clinical improvement was significant with meticulous use of hourly topical natamycin, and oral fluconazole twice a day. The corneal ulcer resolved with the formation of leucomatous corneal opacity. The patient was further registered for penentrating keratoplasty.
Conclusion: This case report lays emphasis on a thorough microbiological work up to provide insightful information thereby expanding our knowledge and spawning new research organisms which may not have been reported earlier. We hereby report a culture proven case of fungal keratitis due to a very rare species; Myriodontium keratinophilum.

Keywords :Fungal keratitis, Myriodontium keratinophilum, Fungal Corneal ulcer