Delhi Journal of Ophthalmology

Correlation Between Serum Lipids and Primary Open Angle Glaucoma: A Clinical Study

Mihika Dube1, P.K. Chhawania2, Abha Shukla2, Rashmi Kujur2, U.S. Tiwari21Department of Ophthalmology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India2Department of Ophthalmology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.


Corresponding Author:

Mihika Dube MBBS, MS
A-41, Emerald Park City,Bhopal,
Madhya Pradesh,India
Email id: mihikadube@gmail.com


Received: 20-JAN-2019 Accepted: 02-MAR-2019 Published Online: 05-MAY-2019
DOI: https://dx.doi.org/10.7869/djo.444

Abstract
Background: Glaucoma is a leading cause of blindness worldwide. Intraocular pressure is the primary risk factor. But in spite of control of intraocular pressure, some cases progress which strengthens the view that there must be other independent risk factors in pathogenesis of glaucoma. Serums lipids have been found to be associated with glaucoma in few studies. We carried out the present study to study the relation between serum lipids and Primary Open Angle Glaucoma (POAG).
Materials and Methods: This study was conducted on 40 patients with POAG and 40 individuals without glaucoma (controls). Ophthalmic examination was performed in all the patients and fasting lipid profile including total cholesterol, triglycerides, Low Density Lipoproteins (LDL) and High Density Lipoproteins (HDL) were measured and analysed between the cases and controls.
Results: Level of total cholesterol, total triglycerides, and LDL were significantly higher in cases than in controls with p value < 0.05. Level of HDL was lower in cases than in controls but it was not statistically significant.
Conclusion: Dyslipidemia is an independent risk factor for POAG. High serum cholesterol, high serum triglycerides and high serum LDL correlate significantly with POAG.

Keywords :Primary open angle glaucoma, Lipids, Dyslipidemia, Correlation