Delhi Journal of Ophthalmology

Corneal Melt with Perforation Following Topical Mitomycin-C Application in Pterygium Excision

Shashidhar Banigallapati, Akhil Bevara
Sankara Eye Hospital, Guntur, Andhra Pradesh, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.

Corresponding Author:

Shashidhar Banigallapati
Sankara Eye Hospital, Vijayawada - Guntur Expressway, Pedakakani, Guntur, Andhra Pradesh - 522509, India
Email id:

Received: 28-DEC-2018 Accepted: 27-JUL-2019 Published Online: 27-FEB-2020

We report a case of corneal melt with perforation due to Mitomycin-C application during Pterygium excision. A 50-year-old male presented with sudden gross diminution of vision and pain in the left eye since one day. He underwent primary Pterygium excision using a bare sclera technique combined with application of Mitomycin-C to the scleral bed intra-operatively in the left eye 40 days back elsewhere.At the site of pterygium head excision, the cornea showed a 3 × 3 mm perforation with iris prolapse through it. Patient was diagnosed as Corneal perforation post Mitomycin-C application and an immediate full thickness corneal patch grafting was performed in the left eye.

Keywords :Mitomycin-C, corneal melt, corneal perforation, corneal patch graft, pterygium excision, bare sclera technique