Delhi Journal of Ophthalmology

Insights Into Infrared Autofluorescence for Monitoring of Optic Disc Melanocytoma

Apoorva Ayachit, Sopan Gupte, Shrinivas Joshi, Guruprasad Ayachit
Department of Vitreoretina, M M Joshi Eye Institute, Hubballi, Karnataka, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.


Corresponding Author:

Apoorva Ayachit
MS, FVRS
Department of Vitreoretina, 
M M Joshi Eye Institute, Gokul Road, Hubballi, Karnataka, India
Email id: apoorva.ag@gmail.com


Received: 07-AUG-2019 Accepted: 05-SEP-2019 Published Online: 27-FEB-2020
DOI: https://dx.doi.org/10.7869/djo.506

Abstract
A case report describing infrared autofluorescence findings in a case of optic disc melanocytoma (ODM): A 42 year old asymptomatic woman was diagnosed to have ODM in the left eye. Two years later, growth in the lesion was noted clinically. On infrared autofluorescence (IR-AF) imaging the lesion showed hypo-autofluorescence corresponding to the area of the pre-existing lesion surrounded by a more hyperautofluorescent arc temporally corresponding to the area of growth. We hypothesize that melanophagosome activity depleted the melanin content of the tumor which led to hypo IR-AF in a melanocytoma. Optical coherence tomography also contributed to the understanding of the infrared autofluorescence findings.

Keywords :Optic disc melanocytoma, infrared autofluorescence, optical coherence tomography