Delhi Journal of Ophthalmology

A Color Doppler Imaging Study of Ocular Haemodynamic Parameters in Primary Open Angle Glaucoma (POAG)

Atif Rahman Raini1, Mohd Masjood2, Humayoun Ashraf3, Mohd. Ashraf3, Mohd. Khalid4
1Department of Ophthalmology, Christian Medical Hospital, Kasganj, Uttar Pradesh, India 
2Government Medical College, Haldwani, Uttarakhand, India 
3Institute of Ophthalmology, J N Medical College, AMU, Aligarh, Uttar Pradesh, India 
4Department of Radio-Diagnosis, J N Medical College, AMU, Aligarh, Uttar Pradesh, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.


Corresponding Author:

Mohd Masjood (MS Ophthalmology)
Government Medical College, 
Haldwani, Uttarakhand, India
Email id: masjood.aligarh@gmail.com


Received: 18-JUL-2019 Accepted: 22-OCT-2019 Published Online: 09-MAY-2020
DOI: https://dx.doi.org/10.7869/djo.520

Abstract
Aims: To study retrobulbar haemodynamics in primary open angle glaucoma (POAG) patients.
Methods: It was a hospital based cross-sectional study carried out in Medical College Out Patient Department (OPD). A total of 26 patients with newly diagnosed POAG and 23 controls were randomly selected for the study. The haemodynamic parameters i.e. Peak systolic velocity (PSV), End diastolic velocity (EDV) and resistivity index (RI) were studied in ophthalmic artery (OA), central retinal artery (CRA) and short posterior ciliary arteries (SPCA) measured using Color Doppler imaging (CDI). Mean, standard deviation (SD) and Independent t- test was applied to compare the results between the two group.
Results: The mean intraocular pressure (IOP) for the POAG group and control group was 26.31±4.51 mmHg and 17.04±1.26 mmHg, respectively (P < 0.001). The mean PSV for both OA and CRA, the mean EDV for all OA, CRA and SPCA were significantly lower whereas the mean RI in the CRA and SPCA were significantly higher in POAG than controls.
Conclusions: Retrobulbar blood flow was significantly lower in POAG as compared to controls, thereby suggesting the importance of measuring the retrobulbar blood flow in POAG patients.

Keywords :Color Doppler imaging (CDI), Primary open angle glaucoma ( POAG), End diastolic velocity (EDV), Peak systolic velocity (PSV), Resistivity index (RI), Retro bulbar blood flow, Ocular Haemodynamic Parameters