Delhi Journal of Ophthalmology

Visual Outcome In Patients of Indirect Traumatic Optic Neuropathy Treated with Steroids

Menezes Valerie1, Usgaonkar Ugam1, Menezes Ramona2
1Department of Ophthalmology, Goa Medical College, Goa, India 
2Department of Radiology, Goa Medical College, Goa, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.

Corresponding Author:

Menezes Valerie (MS)
Siddarth Apartments - 2/S-2, Tonca, P.O Caranzalem - 403002, Goa, India
Email id:

Received: 22-APR-2019 Accepted: 11-DEC-2019 Published Online: 21-JUN-2020

Background: Indirect Traumatic Optic Neuropathy (TON) is an important cause of visual morbidity which may be reversible. 
Aims: To assess the Visual Outcome in patients with Indirect TON Treated With Steroids.
Settings and Design: Prospective Non Randomised Study.
Methods and Material: 34 patients, having mild Traumatic Brain Injury (TBI) with unilateral indirect TON were included. All patients received treatment with Methyl prednisolone 1 gm IV/day for 3 days followed by oral prednisolone 1 mg/kg for 11 days. Patients were divided into 2 groups. Group 1 included 17 patients who received steroids within 72 hours of injury. Group 2 included 17 patients who received steroids after 72 hours of injury.
Statistical analysis used: The Wilcoxon Signed Rank Test was used as the statistical test for visual acuity improvement for each of the groups. Fischer’s exact test was used to assess statistical significance of visual acuity improvement between the 2 groups.
Results: At 1 month follow up, 14 of 17 patients in Group 1 (82.4%) and 12 of 17 patients in Group 2 (70.6%) showed improvement in Visual Acuity which was statistically significant. The difference in visual acuity improvement between the two groups was not statistically significant.
Conclusions: In patients of indirect TON having mild TBI, high dose steroids optimized the visual acuity, without any adverse effects, both in patients who presented within 72 hours and beyond 72 hours of injury.

Keywords :Traumatic Optic Neuropathy, Steroids