Bronchodilator nebulization is one of the most commonly administered treatment for an acute attack of reactive airway disease. Development of acute angle closure glaucoma following nebulization therapy is a rare occurrence. We report a case of acute angle closure of both eyes in a 54 year old gentleman shortly after receiving therapy with inhaled salbutamol and ipratropium. This patient presented to our tertiary care eye hospital and was immediately treated with medical management and laser iridotomy. This case report highlights this rare but possible side effect of inhaled bronchodilator therapy. Health care providers need to be aware of this uncommon adverse effect and appropriate preventive measures such as identifying at risk individuals, usage of protective eye-wear, etc should be practiced.