Delhi Journal of Ophthalmology

Comparison of Angiography Performance of Low-cost portable Fundus camera with standard FFA camera – Validation Study

Deependra Vikram Singh, Gaurav Mathur, Rishi Bhardwaj,  Ajay Sharma 
Retina Department of Eye-Q Superspecialty Eye Hospitals, Sushant Lok, Gurugram, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.


Corresponding Author:

Deependra Vikram Singh, MD
Eye-Q Superspecialty Eye Hospitals
H.NO – 522, Sec-27. Sushant Lok, Gurugram, India, 122002
Email - deependravsingh@hotmail.com


Received: 30-MAR-2020 Accepted: 07-JUN-2020 Published Online: 20-DEC-2020
DOI: https://dx.doi.org/10.7869/djo.594

Abstract
Study Design: In an observational cross-sectional study, 91 eyes of 46 consecutive patients underwent simultaneous Fundus Fluorescein Angiography (FFA) for common retinal disorders. The FFA images captured by both cameras were graded by 3 Retinologists (DVS, GM, RB) in a structured format. 7 characteristics of FFA images that were used for grading were Foveal Avascular Zone (FAZ) visualization, identifying branch retinal vein, Identification of any abnormal hyper fluorescence at macula, Identification of Micro aneurysms, Identification of capillary non perfusion areas and identification of leakage from retinal neovascularization, Image quality and Impact on Clinical decision. Results were captured and statistically analyzed for interobserver and intercamera agreements. 

Results: Out of total 7 features in FFA images graded by 3 Retinologists, 4 characteristics were found to have statistically significant intercamera agreement for 3 retinologists. These were Identification of any abnormal hyper fluorescence at macula, Identification of Micro aneurysms, Identification of capillary non perfusion areas and identification of leakage from retinal neovascularization. These 4 characteristics also had very good agreement between 3 retinologists. 

Conclusion: Based on this pilot study, we can conclude that the Fluorescein Angiography performance of this low-cost portable Fundus camera for detecting clinically relevant findings was comparable to a standard Fundus camera. We conclude that in resource limited settings, this low-cost portable Fundus camera can be a useful alternative to standard Fundus camera for treating common retinal disorders..

Keywords :Low-cost Fundus Fluorescein Angiography, Portable Fluorescein Angiography, Diabetic Retinopathy, Hyperfluorescence