Delhi Journal of Ophthalmology

Reliability of OCT Assisted RNFL Thickness In Diagnosing Glaucoma In High Myopia

Neha Yadav, Aanshu Sahai, Raj Kumar Sharma, Mohd. Abid Shamshad, Salani Gupta, Yamni Singhal
Sahai hospital and research centre, Bhabha Marg, Moti Dungri, Jaipur, Rajasthan, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.


Corresponding Author:

Neha Yadav (M.B.B.S) 
Sahai Hospital and Research Centre
SP-15 Bhabha Marg, Moti Dungri, Jaipur, Rajasthan, India 
E-mail: neha24nupur@gmail.com


Received: 11-MAR-2019 Accepted: 17-MAY-2020 Published Online: 20-DEC-2020
DOI: https://dx.doi.org/10.7869/djo.590

Abstract
Aim : To assess RNFL Thickness in high myopes and evaluating its reliability in diagnosing glaucoma.

Material And Methods: This is a cross-sectional study to compare retinal nerve fibre layer thickness (RNFL) in 112 eyes of 56 subjects presenting to our centre from May 2017 to March 2018. They were divided in two groups based on their refractive status (emmetropes and high myopes >-6D). Baseline ocular examination and Fourier domain optical coherence tomography was done and average and quadrant wise RNFL thickness was measured. Both the groups were compared based on their RNFL thickness. Data was analyzed using unpaired t- test, chi-square test/Fisher exact test wherever applicable. P-value ?0.05 was taken as significant.

Results: Mean RNFL thickness was 85.40±15.45µ in myopes and99.34±10.26µ in emmetropes. It was significantly less (Mean difference 13.94; 95% CI -18.93 to -8.94) in myopes compared to emmetropes. Quadrant wise analysis showed significant thinning in myopes in comparison to emmetropes except in temporal quadrant.

Conclusion: Though OCT is a valuable tool for diagnosing pre-perimetric glaucomatous changes but we have to be very cautious in cases of myopia. There is definite thinning of RNFL in high myopes but we must correlate with the clinical findings. Though the specific pattern of glaucomatous changes can provide clue to differentiate myopic thinning from true glaucomatous thinning which is more generalized butwe should not rely only on OCT with the current normative data.

Keywords :High Myopia, OCT, RNFL Thickness, Glaucoma