Purpose: To evaluate association between visual acuity (VA) and macular thickness (MT) measured by Cirrus Optical Coherence Tomography (OCT) in patients of early and advanced stages of primary open angle glaucoma (POAG). 

Material Method: A cross section observational study was conducted between 2016-2019. All POAG patients aged >40 years attending our hospital were study population. Uncorrected visual acuity (UCVA) and Best corrected Visual acuity (BCVA) was noted. Anterior and posterior segment assessment was done. Cirrus OCT was used to measure MT. POAG was grouped as early and advanced. P values < 0.05 was considered statistically significant. 

Results: 155 patients were examined.72 (46.5%) of them were in early POAG stage and rest 83(53.5%) belonged to advanced stage. The mean age was 63.46 ± 8.5 years and Male patients were 91 (58.7%). Association of BCVA with stages of POAG was found to be statistically significant (P=<0.001) and it was worst in advance POAG. Association of mean MT with stages of POAG was statistically significant (P<0.001) and it was less in advanced POAG. Range of mean deviation (MD) with stage of POAG was found to be statistically significant (P<0.001). Association of MT with BCVA among overall study was reported to be statistically significant (P=0.006). Association of MD with BCVA among overall study was statistically significant (P=<0.001). 

Conclusion: Among POAG patients enrolled in the study an inverse correlation between BCVA & MT and BCVA & MD was observed. Level of correlation was mild and strong for MT and MD respectively. Correlation was found to be statistically significant.