Delhi Journal of Ophthalmology

Resolution of Combined Hamartoma of Retina And Retinal Pigment Epithelium (CHRRPE) with Following Pars Plana Vitrectomy

Monika Kapoor1, Siddharth Madan2, Priyanka Sankaran1, Preeti Singh1, Sarita Beri1
1Department of Ophthalmology, Lady Hardinge Medical college and Associated Hospitals, University of Delhi, New Delhi, India
2Department of Ophthalmology, University College of Medical Sciences and Associated GTB Hospital, University of Delhi, New Delhi, India

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.


Corresponding Author:

Siddharth Madan 
MS, DNB, FICO, FAICO (Retina) 
Assistant Professor, 
Department of Ophthalmology, University College of Medical 
Sciences and Associated GTB Hospital, University of Delhi, New Delhi
Email: drsiddharthmadan@gmail.com


Received: 06-FEB-2021 Accepted: 02-APR-2021 Published Online: 05-OCT-2021
DOI: https://dx.doi.org/10.7869/djo-695

Abstract
Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) is a benign tumor located at the posterior pole. The pathogenesis of the lesion is unknown however some authors propose that the tumor may arise from undifferentiated ectopic progenitor cells which were otherwise destined for RPE and demonstrate failure to completely differentiate. These cells then undergo hyperplasia and accumulate in the neurosensory retina. Optical coherence tomography (OCT) assists in classification of the lesions based on location and differentiates from an epiretinal membrane (ERM). Surgical intervention is warranted in cases that produce macular distortion with/without associated ERM or retinal detachment and those producing visual complaints. Similar was the case with a 26-year-old male who presented with unilateral metamorphopsia that was attributed to CHRRPE with a grade two ERM. Pars plana vitrectomy with ERM peeling resulted in resolution of disabling symptoms and anatomical success as visible on OCT.

Keywords :CHRRPE, Epiretinal Membrane, Combined Hamartoma Of Retina And Retinal Pigment Epithelium, Pars Plana Vitrectomy, Omega Sign