Delhi Journal of Ophthalmology

Prevalence of Dry Eyes in Postmenopausal Females in Hadoti Region of Rajasthan

Jaishree Singh1, Ashok Kumar Meena1,Tarun Gupta2, Ekta Garg2, Pushkar Dhir2, Neeraj Aggarwal3
1Department of Ophthalmology, Government Medical College, Kota, Rajasthan, India.
2Department of Ophthalmology, Dhir Hospital & Eye Institute, Bhiwani, Haryana, India.
3Department of Ophthalmology, Sri Jagdamba Charitable Eye Hospital, Ganganagar, Rajasthan, India.

Editor-in-Chief, Delhi Journal of Ophthalmology, Dr R.P.Centre, AIIMS.


Corresponding Author:

Tarun Gupta (MS)
Department of Ophthalmology, 
Dhir Hospital & Eye Institute, Bhiwani, Haryana, India
E-mail: tarun13doc@gmail.com


Received: 09-MAY-2019 Accepted: 07-JUL-2020 Published Online: 25-JUN-2022
DOI: https://dx.doi.org/10.7869/djo.764

Abstract
Introduction: Dry eye syndrome (DES) is one of the most frequently encountered ocular conditions. Although clinical observation has long been suggested that DES is more common in women, particularly among older women, there are only few epidemiological studies which are available to describe the magnitude of the problem of DES among post-menopausal women especially in India.

Materials and Method: A total of 200 post-menopausal females attending the Out Patient Department were included in the study. All patients were given Ocular Surface Disease Index (OSDI) questionnaire. Diagnosis of dry eye in our study was made when two of the 3 tests are positive viz. Schirmer-I test (<10mm), Tear Film Break –Up Time (TBUT) (<10sec) and Ocular surface dye staining with Lissamine green dye (Van Bjisterveld’s score =4). 

Results: Prevalence of dry eye syndrome was high in this age group i.e. 44% (88/200 post-menopausal women(PMW). 49% (98 Post Menopausal Women) responded with symptoms of dry eye (OSDI score >12). Tear Film Break-Up Time test sensitivity was 97.6% and specificity was 92.36%. Lissamine Green dye staining was less sensitive but more specific test to diagnose dry eye syndrome (sensitivity of 33.6% and specificity of 98.91%). Schirmer I test has high sensitivity (91.2 %) and high specificity (96.36%). The positive predictive value was 91.94% and negative predictive value was 96.01%. All three tests were reliable in diagnosing dry eye as each had p value < 0.001. Meibomian Gland Dysfunction was present in 10%of Dry eye positive females.

Conclusion: The high prevalence of dry eye in post-menopausal females is responsible for significant morbidity..

Keywords :Dry Eye Disease, Postmenopausal Females, Prevalence, Osdi, Schirmer, TBUT